Biology (AKU-BIO)
Topic 2 of 4Aga Khan Board

Human Body Systems

Circulatory, digestive and respiratory systems

What You'll Learn
Arteries: away from heart; veins: to heart (have valves)Small intestine villi: large surface area for absorptionAlveoli: large surface area, thin walls for gas exchangeInspiration: diaphragm contracts, lung volume increases

Circulatory System:

The heart is a double pump. Right side pumps deoxygenated blood to the lungs. Left side pumps oxygenated blood to the body.

  • Arteries: thick-walled, carry blood away from heart, high pressure
  • Veins: thinner walls, carry blood to heart, have valves to prevent backflow
  • Capillaries: one cell thick, allow exchange of oxygen, nutrients and CO₂

Digestive System (mouth to anus):

Mouth (chewing + amylase) → oesophagus → stomach (HCl + protease) → small intestine (absorption of nutrients via villi — large surface area, thin walls, rich blood supply) → large intestine (water absorption) → rectum → anus.


Respiratory System:

Air: nose → trachea → bronchi → bronchioles → alveoli (gas exchange).

Alveoli have: large surface area, thin walls (one cell thick), moist, good blood supply → efficient diffusion of O₂ into blood, CO₂ out.

Breathing in (inspiration): diaphragm contracts (flattens), rib cage rises → lung volume increases → pressure drops → air enters.

Breathing out (expiration): diaphragm relaxes, rib cage falls → air expelled.

Key Points to Remember

  • 1Arteries: away from heart; veins: to heart (have valves)
  • 2Small intestine villi: large surface area for absorption
  • 3Alveoli: large surface area, thin walls for gas exchange
  • 4Inspiration: diaphragm contracts, lung volume increases

Pakistan Example

Shaukat Khanum Hospital — Human Systems and Cancer Treatment

Shaukat Khanum Memorial Cancer Hospital in Lahore treats lung cancer (respiratory system), bowel cancer (digestive system), and heart disease (circulatory system). AKU-EB Biology questions often use Pakistani hospital contexts. Understanding the structure of alveoli explains why smoking causes cancer — tar destroys the thin alveolar walls reducing gas exchange efficiency.

Quick Revision Infographic

Biology — Quick Revision

Human Body Systems

Key Concepts

1Arteries: away from heart; veins: to heart (have valves)
2Small intestine villi: large surface area for absorption
3Alveoli: large surface area, thin walls for gas exchange
4Inspiration: diaphragm contracts, lung volume increases
Pakistan Example

Shaukat Khanum Hospital — Human Systems and Cancer Treatment

Shaukat Khanum Memorial Cancer Hospital in Lahore treats lung cancer (respiratory system), bowel cancer (digestive system), and heart disease (circulatory system). AKU-EB Biology questions often use Pakistani hospital contexts. Understanding the structure of alveoli explains why smoking causes cancer — tar destroys the thin alveolar walls reducing gas exchange efficiency.

SeekhoAsaan.com — Free RevisionHuman Body Systems Infographic

Test Your Knowledge!

3 questions to test your understanding.

Start Quiz